陈吾雅简介

陈吾雅

男，理学博士，口腔系，特聘青年研究员

研究方向：1. 仿生生物医用材料

2. 干细胞与组织工程

3. 口腔疾病与纳米材料

2018年7月毕业于华南师范大学生命科学学院，细胞生物学专业，细胞信号转导方向。博士研究生期间主要从事生物材料与组织工程领域的基础理论研究。

现为佛山科学技术学院口腔医学院特聘青年研究员，开展生物材料相关研究工作。主要采用组织工程学研究策略，设计和制备多种仿生生物材料治疗口腔相关疾病，如牙髓炎、龋病、颅颌面创伤等。并研究治疗与修复过程涉及的细胞和分子学机理。

当前，以第一作者身份发表SCI论文2篇，参与SCI论文发表13篇，授权国家发明专利1项。博士研究生期间，参与导师主持国家或省部级课题多项。2016年获得博士研究生国家奖学金。

发表论文：

1. Q. Ban, W.
   Chen, S. Du, H. Wang, J. Li, R. You, Y. Jin, Y. Xue, Y.Q. Guan, The
   preparation of the ordered pores colloidal crystal scaffold and its role in
   promoting growth of lung cells, Colloids
   Surfaces B Biointerfaces. 173 (2019) 907–917.

2. W. Chen, W.
   Wang, L. Chen, J. Chen, X. Lu, Z. Li, B. Wu, L. Yin, Y.Q. Guan, Long-term
   G1cell cycle arrest in cervical cancer cells induced by co-immobilized TNF-α
   plus IFN-γ polymeric drugs, J. Mater.
   Chem. B. 6 (2018) 327–336.

3. K. Hu, X. Chen, W. Chen, L. Zhang, J. Li, J. Ye, Y. Zhang, L. Zhang, C.H. Li, L.
   Yin, Y.Q. Guan, Neuroprotective effect of gold nanoparticles composites in
   Parkinson’s disease model, Nanomedicine
   Nanotechnology, Biol. Med. 14 (2018) 1123–1136.

4. L. Yin, Z. Meng, Y. Zhang, K. Hu, W. Chen, K. Han, B.Y. Wu, R. You, C.H.
   Li, Y. Jin, Y.Q. Guan, Bacillus spore-based oral carriers loading curcumin for
   the therapy of colon cancer, J. Control.
   Release. 271 (2018) 31–44.

5. L.K. Zhang, H. Wang, R. Yang, M. Liu, Q. Ban, W. Chen, M. Zhao, R. You, Y. Jin, Y.Q.
   Guan, Bone marrow stem cells combined with polycaprolactone-polylactic
   acid-polypropylene amine scaffolds for the treatment of acute liver failure, Chem. Eng. J. 360 (2018) 1564–1576.

6. S.W. Du, L.K. Zhang, K. Han, S. Chen, Z. Hu, W. Chen, K. Hu, L. Yin, B. Wu, Y.Q.
   Guan, Combined Phycocyanin and Hematoporphyrin Monomethyl Ether for Breast
   Cancer Treatment via Photosensitizers Modified Fe3O4Nanoparticles Inhibiting
   the Proliferation and Migration of MCF-7 Cells, Biomacromolecules. 19 (2018) 31–41.

7. M. Zhao, L. Chen, W. Chen, Z. Meng, K. Hu, S. Du, L. Zhang, L. Yin, B. Wu, Y.-Q.
   Guan, Packaging cordycepin phycocyanin micelles for the inhibition of brain
   cancer, J. Mater. Chem. B. 5 (2017)
   6016–6026.

8. L. Zhang, Y.X. Zhang, J.N. Qiu, J. Li, W. Chen, Y.Q. Guan, Preparation and
   Characterization of Hypoglycemic Nanoparticles for Oral Insulin Delivery, Biomacromolecules. 18 (2017) 4281–4291.

9. S. Niu, L.K. Zhang, L. Zhang, S. Zhuang, X. Zhan, W.Y. Chen, S. Du, L. Yin, R. You, C.H.
   Li, Y.Q. Guan, Inhibition by multifunctional magnetic nanoparticles loaded with
   alpha-synuclein RNAi plasmid in a Parkinson’s disease model, Theranostics. 7 (2017) 344–356.

10. W.Y. Chen, R.C.
    Yang, H.M. Wang, L. Zhang, K. Hu, C.H. Li, R. You, L. Yin, Y.Q. Guan,
    Self-Assembled Heterojunction Carbon Nanotubes Synergizing with
    Photoimmobilized IGF-1 Inhibit Cellular Senescence, Adv. Healthc. Mater. 5 (2016) 2413–2426.

11. L. Zhang, W. Cai, W.Y. Chen, L. Zhang, K. Hu, Y.Q. Guan, Synthesis of AzPhchitosan-bifenthrin-PVC
    to protect cables against termites, Carbohydr.
    Polym. 139 (2016) 50–60.

12. L. Wu, K. Hu, L. Zhang, W. Chen, X. Chen, R. You, L. Yin, Y.Q. Guan, Preparation and
    characterization of latex films photo-immobilized with IFN-α, Colloids Surfaces B Biointerfaces. 145
    (2016) 104–113.

13. R. Yang, L. Wu, J. Chen, W. Chen, L. Zhang, L. Zhang, R. You, L. Yin, C.H. Li, Y.Q. Guan,
    Effects of Differentiation and Antisenescence from BMSCs to Hepatocy-Like Cells
    of the PAAm-IGF-1/TNF-α Biomaterial, ACS
    Appl. Mater. Interfaces. 8 (2016) 26638–26647.

授权专利：

1. 关燕清，刘俊明，陈吾雅。一种抗细胞衰老的骨组织工程支架材料及其应用。专利号201410173890.6