温峰（硕士生导师）
姓名：温峰
性别： 男
职称：JN江南官方 教授
个人荣誉：
Hall of Fame Scholar, Mississippi State University, 2018；
“优秀研究生导师”，佛山科学技术学院，2022;
教育与工作简历：
2010年毕业于吉林大学畜牧兽医学院，获学士学位；导师：张乃生 教授。
2013年毕业于中国农业科学院上海兽医研究所，获硕士学位；导师：童光志 研究员。
2018年毕业于美国Mississippi State University兽医学院，获哲学博士学位；导师：万秀峰 教授。
2019年至今，JN江南官方，生命科学与工程学院，兽医系，特聘教授、教授、岭南学者。
主要研究内容和研究成果
从事动物流感病毒相关基础与应用研究工作，主要包括流感病毒与宿主细胞互作相关分子机制、病毒疫苗的研制、病毒跨种传播机制等研究。以第一或通讯作者（含共同）在Journal of Infection(9篇)、Nature Communications (1篇)、Journal of Virology(4篇)、Trends in Microbiology(1篇)、mBio(1篇)、Emerging Infectious Diseases(1篇)、Eurosurveillance(1篇)、Virulence(1篇)和Poultry Science(4篇)等主流权威期刊共发表SCI论文三十余篇。
教学与人才培养：
承担《兽医生物制品学》、《生物制品技术》等课程。
社会兼职：
佛山科学技术学院知联会副会长
Virology Journal（三区，IF2022=5.9）Associate editor
Frontiers in Immunology（二区，IF2022=8.7）、BMC Veterinary Research（二区，IF2022=2.7）和PLoS ONE（三区，IF2022=3.7）Editor
中国畜牧兽医学会高级会员
世界家禽学会会员
美国病毒学会会员
美国糖生物学会会员
广东省畜牧兽医学会会员
广东省科技咨询专家库成员
广东省高层次人才评审专家库成员
佛山市青少年科技创新大赛专家库，评审专家
国家自然科学基金与广东省自然科学基金评审专家库成员
主持项目：
先后主持国家自然科学基金青年基金、广东省自然科学基金面上项目(3项）、广东省医学科研基金、广东省教育厅特色创新项目、佛山科学技术学院动物新发疫病防控重点实验室开放基金、佛山科学技术学院高层次人才启动基金和佛山市博士后启动基金等多项研究基金；参与多项国自然基金与美国国立卫生研究院基金项目。
近年部分论文：
1. Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J, Yu H, Liu Q, Huang S. 2024. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol 10.1128/jvi.00248-24.
2. Wen F, Li L, Zhao N, Chiang MJ, Xie H, Cooley J, Webby R, Wang PG, Wan XF. 2018. A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells. J Virol 92.(2):e01621-17.
3. Wen F, Blackmon S, Olivier AK, Li L, Guan M, Sun H, Wang PG, Wan XF. 2018. Mutation W222L at the Receptor Binding Site of Hemagglutinin Could Facilitate Viral Adaption from Equine Influenza A(H3N8) Virus to Dogs. J Virol 92(18):e01115-18.
4. Guo J, He J, Liang Z, Huang S, Wen F. 2024. Birds as reservoirs: unraveling the global spread of Gammaand Deltacoronaviruses. mBio 10.1128/mbio.02324-24.
5. Gao C, Wen F, Guan M, Hatuwal B, Li L, Praena B, Tang CY, Zhang J, Luo F, Xie H, Webby R, Tao YJ, Wan XF. 2024. MAIVeSS: streamlined selection of antigenically matched, high-yield viruses for seasonal influenza vaccine production. Nat Commun 15:1128.
6. Yan Z, Li Y, Huang S, Wen F. 2023. Global distribution, receptor binding, and cross-species transmission of H6 influenza viruses: risks and implications for humans. J Virol 97:e0137023.
7. Zhang X, Chen G, Liu R, Guo J, Mei K, Qin L, Li Z, Yuan S, Huang S, Wen F. 2024. Identification, pathological, and genomic characterization of novel goose reovirus associated with liver necrosis in geese, China. Poult Sci 103:103269.
8. Wen F, Wang C, Guo J, Yu H, Yuan S, Li Y, Li Z, Huang S, Liang Z. 2024. Development and application of a triplex real-time PCR assay for the detection of H3, H4, and H5 subtypes of avian influenza virus. Poult Sci 103:103333.
9. Liu J, Liang Z, Sun W, Hua W, Huang S, Wen F. The H4 subtype of avian influenza virus: a review of its historical evolution, global distribution, adaptive mutations and receptor binding properties. Poult Sci. 2024 Aug;103(8):103913.
10. Wen F, Chen G, Guo J, Guan M, Li Z, Yu H, Li J, Liu Q, Huang S. 2023. Identification of a duck H9N2 influenza virus possessing tri-basic hemagglutinin cleavage sites genetically close to the human H9N2 isolates in China, 2022. J Infect 86:e153-e155.
11. Liu L, Chen G, Huang S, Wen F. 2023. Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research Advances. Virulence 14:2235459.
12. Yuan S, Cheng Q, Guo J, Li Z, Yang J, Wang C, Liang Z, Zhang X, Yu H, Li Y, Huang S, Wen F. 2022. Detection and genetic characterization of novel infectious bronchitis viruses from recent outbreaks in broiler and layer chicken flocks in southern China, 2021. Poult Sci 101:102082.
13. Wen F, Wan XF. 2019. Influenza Neuraminidase: Underrated Role in Receptor Binding. Trends Microbiol 27:477-479.
14. Wen F, Zhang X, Guo J, Liang Z, Cheng Q, Wang C, Yu H, Du Y, Huang S, Li J, Li Y. 2022. Emergence of H3N8 avian influenza viruses possessing tri-basic hemagglutinin cleavage sites in China. J Infect 85:e112-e114.
15. Wang SY, Wen F, Yu LX, Wang J, Wang MZ, Yan JC, Zhou YJ, Tong W, Shan TL, Li GX, Zheng H, Liu CL, Kong N, Tong GZ, Yu H. 2022. Potential Threats to Human Health from Eurasian Avian-Like Swine Influenza A(H1N1) Virus and Its Reassortants. Emerg Infect Dis 28:1489-1493.
16. Guo J, Wang C, Huang S, Wen F. Letter to the editor: Sequencing bias for residue 28 of the neuraminidase of the recent highly pathogenic avian influenza virus A(H5N8). Euro Surveill. 2021 Sep;26(36):2100829. doi: 10.2807/1560-7917.
17. Yang J, Li Y, Guo J, Luo K, Yu H, Chen Y, Li A, Yuan S, El-Ashram S, Huang S, Wen F. 2021. Genetic characterization of an H5N6 avian influenza virus from chickens in Guangdong, China. J Infect 82:414-451.
18. Guo J, Yu H, Yang J, Li Y, Zhang X, Mei K, Chi S, Yuan S, Liu H, El-Ashram S, Huang S, Wen F. 2021. Weighted gene co-expression network analysis revealed host transcriptional response to H1N1 influenza A virus infection. J Infect 82:e4-e7.
19. Guo J, Yu H, Wang C, Yuan S, Sun H, Yang J, Cheng Q, Luo K, Li Y, Li Z, Liu Q, Huang S, Wen F. 2021. Re-emergence of highly pathogenic avian influenza A(H5N8) virus in domestic Goose, China. J Infect 83:709-737.
20. Wen F, Yu H, Guo J, Li Y, Luo K, Huang S. 2020. Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2. J Infect 80:671-693.
21. Wen F, Li W, Guo J, Yang J, Zhang X, Mei K, Liu H, El-Ashram S, Luo K, Yuan S, Chi S, Huang S. 2020. Genetic characterization of a novel genotype H9N2 avian influenza virus from chicken in South China. J Infect 81:816-846.
22. Wen F, Huang S, Guo J. 2020. Egg adaptive mutation patterns of H3N2 human influenza A viruses. J Infect 80:232-254.
23. Wang XH, Gong XQ, Wen F, Ruan BY, Yu LX, Liu XM, Wang Q, Wang SY, Wang J, Zhang YF, Zhou YJ, Shan TL, Tong W, Zheng H, Kong N, Yu H, Tong GZ. 2020. The role of PA-X C-terminal 20 residues of classical swine influenza virus in its replication and pathogenicity. Vet Microbiol 251:108916.
24. Guo J, Huang S, Wen F. 2020. Identification of coevolution sites and evolution history for neuraminidase of human influenza A viruses. J Infect 80:232-254.
25. Wen F, Guo J, Huang S. 2019. A meta-analysis identified genes responsible for distinct immune responses to trivalent inactivated and live attenuated influenza vaccines. J Cell Physiol 234:5196-5202.
26. Ruan BY, Wen F, Gong XQ, Liu XM, Wang Q, Yu LX, Wang SY, Zhang P, Yang HM, Shan TL, Zheng H, Zhou YJ, Tong W, Gao F, Tong GZ, Yu H. 2018. Protective efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the European Avian-like H1N1 swine influenza virus in mice and pigs. Vet Microbiol 222:75-84.
27. Sun H, Blackmon S, Yang G, Waters K, Li T, Tangwangvivat R, Xu Y, Shyu D, Wen F, Cooley J, Senter L, Lin X, Jarman R, Hanson L, Webby R, Wan XF. 2017. Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus. J Virol 91(21):e00637-17.
28. Guan M, Olivier AK, Lu X, Epperson W, Zhang X, Zhong L, Waters K, Mamaliger N, Li L, Wen F, Tao YJ, DeLiberto TJ, Wan XF. 2022. The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype H7 Avian Influenza A Viruses. J Virol 96:e0134422.
29. Han L, Li L, Wen F, Zhong L, Zhang T, Wan XF. 2019. Graph-guided multi-task sparse learning model: a method for identifying antigenic variants of influenza A(H3N2) virus. Bioinformatics 35:77-87.
联系方式：
wenf@fosu.edu.cn
